AI-powered tools

Built on pharmaceutical
science fundamentals

Every tool applies established mathematical frameworks — AI amplifies the analysis, it never replaces the underlying science.

Available now

Formulation Development Optimizer

Enter dissolution data from 2–5 prototypes. The tool automatically fits six release kinetics models, identifies your dominant mechanism, and uses that understanding to suggest the next composition — with specific excipient amounts and a predicted dissolution profile.

  • Six models fitted simultaneously: Zero-order, First-order, Higuchi, Korsmeyer-Peppas, Hixson-Crowell, Weibull
  • R²-ranked comparison with parameter extraction (k, n, kH, Td, b)
  • Mechanistic AI recommendations grounded in fitted kinetics
  • Interactive dissolution chart with per-prototype model fit overlay
  • Bracketing formulation suggestions for design space coverage
  • No account required — data stays in your browser only
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Model fitting — Prototype 2
Korsmeyer-Peppas
0.981
Higuchi
0.912
Weibull
0.847
First-order
0.703
Hixson-Crowell
0.601
Zero-order
0.512
Best fit: anomalous transport (n = 0.67)
Available now

f2 Similarity Calculator

Calculate f1 difference factor and f2 similarity factor between dissolution profiles for bioequivalence and formulation bridging assessments — with automatic FDA and EMA guideline compliance checks.

  • f1 and f2 calculation per FDA 1997 guidance and EMA guidelines
  • Multi-profile comparison (up to 12 test profiles vs one reference)
  • Bootstrap f2 for highly variable dissolution data
  • Automatic timepoint and variability eligibility checks
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f2 Similarity Calculator — live
Available now

DoE Assistant

Generate statistically sound experimental designs for formulation development — full factorial, Box-Behnken, central composite, and D-optimal designs based on your excipient constraints and critical quality attributes.

  • Design type recommendation based on number of factors
  • Constraint-aware run list generation
  • Exportable run order with randomization
  • Response surface interpretation guidance
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DoE Assistant — live
Available now

Shelf Life Predictor

Predict drug product shelf life by fitting Arrhenius kinetics to degradant data from accelerated and intermediate ICH stability conditions. Extrapolates to long-term storage temperature to estimate time to specification failure per ICH Q1A(R2) and Q1E.

  • Arrhenius equation fitting — ln(k) vs 1/T regression across all enabled ICH conditions
  • Supports zero-order and first-order degradation kinetics
  • All four ICH storage zones — 25°C/60%RH, 30°C/65%RH, 40°C/75%RH and more
  • Activation energy (Ea) and Q₁₀ factor calculation with mechanistic interpretation
  • Arrhenius plot and degradant-vs-time chart with extrapolated projection to spec limit
  • AI interpretation grounded in ICH Q1E regulatory context and fitted kinetic parameters
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Arrhenius fit — degradant kinetics
Accelerated (40°C)
R²=0.97
Intermediate (30°C)
R²=0.94
Long-term (25°C)
R²=0.91
Predicted shelf life: 28 months @ 25°C